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What (who) is gut function - definition
![''[[Candida albicans]]'', a dimorphic fungus that grows as a yeast in the gut](https://commons.wikimedia.org/wiki/Special:FilePath/Candida albicans.jpg?width=200 "''[[Candida albicans]]'', a dimorphic fungus that grows as a yeast in the gut")
![[[Microfold cells]] transfer antigens (Ag) from the lumen of the gut to [[gut-associated lymphoid tissue]] (GALT) via [[transcytosis]] and present them to different innate and adaptive immune cells.](https://commons.wikimedia.org/wiki/Special:FilePath/Transvesicular transport by microfold cells.png?width=200 "[[Microfold cells]] transfer antigens (Ag) from the lumen of the gut to [[gut-associated lymphoid tissue]] (GALT) via [[transcytosis]] and present them to different innate and adaptive immune cells.")
![The function mapping each year to its US motor vehicle death count, shown as a [[line chart]]](https://commons.wikimedia.org/wiki/Special:FilePath/Motor vehicle deaths in the US.svg?width=200 "The function mapping each year to its US motor vehicle death count, shown as a [[line chart]]")
![Graph of two trigonometric functions: [[sine]] and [[cosine]].](https://commons.wikimedia.org/wiki/Special:FilePath/Sine cosine one period.svg?width=200 "Graph of two trigonometric functions: [[sine]] and [[cosine]].")
Wikipedia
Intestinal permeability is a term describing the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall, into the rest of the body. The intestine normally exhibits some permeability, which allows nutrients to pass through the gut, while also maintaining a barrier function to keep potentially harmful substances (such as antigens) from leaving the intestine and migrating to the body more widely. In a healthy human intestine, small particles (< 4 Å in radius) can migrate through tight junction claudin pore pathways, and particles up to 10–15 Å (3.5 kDa) can transit through the paracellular space uptake route. There is some evidence abnormally increased intestinal permeability may play a role in some chronic diseases and inflammatory conditions. The most well understood condition with observed increased intestinal permeability is celiac disease.
